MegaSporeBiotic™ is a 100% spore-based, broad-spectrum probiotic clinically shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains efficacy during antibiotic therapy.
Our human clinical trial was published in August 2017 in the Clinical Journal of Gastrointestinal Pathophysiology as a ‘frontier’ study when MegaSporeBiotic significantly reduced lipopolysaccharide (LPS). LPS is the metabolic endotoxin (leaky gut) that is responsible for systemic inflammation which is the source of all chronic illness. LPS was reduced by 45% and triglycerides by 24%, in just one month. This was without diet or lifestyle changes.
Trillions of commensal bacteria in the gastrointestinal tract containLPS, and when these bacteria die, they release LPS into the intestinal lumen. This process happens quite frequently, as many bacteria die off during a meal, but LPS remains harmless inside the intestinal lumen. It is not until LPS reaches the brush border and enters circulation that it begins to trigger low-grade inflammation.
LPS can delay gastric emptying, slow bowel motility, disrupt ghrelin function, inhibit testosterone production, reduce serotonin, and so much more.
MegaPreBiotic™ is the first Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria. MegaPreBiotic™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.